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Collagen Stimulating Injections

Collagen stimulating injections is a skin rejuvenation treatment using a synthetically derived poly-lactic acid polymer.  Also known as "neocollagenesis", this type of injectable is available as a commercial product, and is used to improve the skin's texture and elasticity.  It can also be used to treat post-acne scarring and tissue atrophy.  It can be combined with other rejuvenation treatments such as laser, RF tissue tightening, and gold threads treatment. It can be used on face and the body but not in areas close to bones where soft tissue is very scarce. These types of injections are not used close to eyes and lips.

How does it work?

Synthetic polymers are injected into the skin to activate fibroblasts - the cells that can produce new collagen fibres. The polymer stimulates the cells to generate new collagen, and as a consequence the skin becomes thicker and firmer.  Small scar defects and wrinkles can be smoothed out.  This process is requires patience as it requires a few months to build up enough collagen, and the first results typically become apparent after six weeks.  The maximum results are achieved up to six months.

How is it done?

Skin is numbed with help of a local anaesthetic cream, which is then injected into skin in a series of injections. The treated sites are then massaged to more evenly distribute the active ingredients. Ice packs are then applied to minimize swelling.

Is it painful?

Normally the injections are well tolerated by most people.  The local application of anaesthetic cream also significantly reduces discomfort.

Are there any contraindications?

Collagen generating injections may be contraindicated when the skin suffers from infection or a malignancy.  It is also not advisable to undergo this treatment if the patient has a tendency to form kelloid scars, suffers from autoimmune diseases, or is either pregnant or breastfeeding

Side effects?

Bruising and swelling are possible, but this is temporary and will settle within 2 weeks. Infection is possible, but is very rare.  If it does occur, it will require treatment with antibiotics. Small nodule formation is sometimes noted, however massaging the area normally resolves the problem.


Cooling the treated area after the procedure will reduce swelling and bruising. Patients are advised to apply their usual moisturiser and massage the injected areas for 1-2 weeks at least twice a day. This will prevent lumpiness formation and stimulate active collagen production. After the initial swelling subsides no change is observed till at least 4 weeks, this is because new collagen production is a very slow process and is hindered further in smokers. Make up can be applied next day.

How many treatments are required?

A minimum 2 sessions 6 weeks apart is required, however for 3-4 sessions are advised for the best possible results.

How long does the effect last?

Typically collagen stimulating injections will last up to 2 years, however, repeated treatments tends to improve the duration of the positive effects.

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